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AGE-RELATED MACULAR DEGENERATION

 

Macular Degeneration is an eye condition in which the macula, a sensitive area in the retina responsible for central and detail vision, is damaged, often causing loss of central vision.

Types

"Dry" form — the most common form usually progresses slowly and causes central vision loss.

"Wet" form — rarer, and more severe. May progress rapidly causing significant central vision loss.

Who Gets It?

Most common in people over 50, but can appear as early as age 40. As life expectancy increases, the disease is becoming a significant problem.

Causes

No conclusive proof exists. However, some scientists believe heredity may play a part, as well as UV light exposure and nutrition.

Symptoms

Blurred or fuzzy vision; straight lines, such as sentences on a page or telephone poles, appear wavy; blind spot in the middle of vision.

Prevention

It is now recognised that a diet containing five daily portions of fruit and vegetables is protective for AMD. The role of dietary animal-derived fat is also important, although clear dietary advice is not yet available as to the balance of fats appropriate to prevent AMD.

We also know that hypertension (blood pressure) is a causitive factor, especially in women. Smoking is a potent risk factor for AMD of both types.


Treatment

"Dry" form — No proven effective treatment. Low vision rehabilitation can help those with significant vision loss to maintain excellent quality of life.

"Wet" form — laser surgery or photodynamic therapy may help as well as low vision rehabilitation.

Photodynamic Therapy
Photodynamic therapy (PDT) is one of the most promising new treatments for the "wet" form of macular degeneration. It involves the injection of Visudyne, into the bloodstream, followed by a brief laser treatment. The laser "activates" the drug, which helps destroy abnormal blood vessels in the eye that damage the macula. Several treatments may be necessary for it to be effective.

PDT may become more widely available to patients. However, it is not a good choice for everyone. Your ophthalmologist can tell you if you might be a good candidate for treatment.

Anti-VEGF Agents
Three newer drugs are now being used against Wet AMD. All three (Lucentis, Macugen and Avastin) are given by injection into the eye using a very fine needle. The injections need to be repeated every four to six weeks. If you are interested in receiving treatment for AMD with one of these newer drugs, please contact us to arrange a prior consultation.

Unproven Treatments

Be wary of any treatment that promises to restore vision, cure or prevent macular degeneration. There are many so-called "miracle cures" advertised (often in magazines or on the Internet) that have not been adequately tested for safety or efficacy. These treatments may be expensive and are generally not covered by insurance.

Current Research

There is a great deal of research and several major scientific studies being conducted to find the causes and develop effective treatments for all types of macular degeneration.

Low Vision Rehabilitation

This can help people who have experienced mild to severe vision loss adjust to their condition and continue to enjoy active and independent lifestyles. Rehabilitation may involve anything from adjusting the lighting in your home to learning to use low vision aids to help you read and perform daily tasks.

Certain factors other than hereditary seem to play a role in the development of the disease.

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© Simon Horgan 2002-8   Last updated 7th May, 2008  

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